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You are here: Home / Podcast Episodes / Unraveling the Mysteries of Vitamin B6

Unraveling the Mysteries of Vitamin B6

October 13, 2025 by Dr. Gil Winkelman Leave a Comment

 

In this episode of Ask Dr. Gil, Dr. Gil Winkelman delves into the complexities of Vitamin B6 and its active form, P5P. He clarifies common misconceptions, discusses the importance of proper dosage, and highlights the potential for sensitivities and intolerances. The conversation also touches on the role of B6 in numerous bodily functions and the implications of deficiencies, particularly in relation to mental health. Dr. Winkelman emphasizes the need for a balanced approach to supplementation and the importance of understanding individual health needs.

Unraveling the Mysteries of Vitamin B6Dr. Gil Winkelman
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Takeaways

  • There’s a lot of confusion about B6 and P5P.
  • B6 and P5P are the same vitamin; one is active.
  • Functional deficiency can exist even with normal blood levels.
  • Pyrrole disorder can lead to functional deficiencies in B6.
  • B6 is involved in over 350 reactions in the body.
  • Too much B6 can cause neurological issues.
  • B6 sensitivity can manifest as anxiety and fatigue.
  • Biofilm in the intestines can block nutrient absorption.
  • Histamine issues can complicate B6 supplementation.
  • Taking too much folate can also be harmful.

You can learn more with my online course Eliminate Anxiety Naturally at https://askdrgil.com/reduce-anxiety-naturally-course/. I also offer a shorter, course about why folates make your anxiety worse https://askdrgil.com/methylation-mini-course/ which goes through the methylation cycle in much greater detail.

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Ask Dr. Gil Podcast

Dr. Gil Winkelman ND

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